Anti-androgenic activity of Myricae Cortex--isolation of active constituents from bark of Myrica rubra.
نویسندگان
چکیده
The aqueous ethanol extract of Myricae Cortex (bark of Myrica rubra Sieb. et Zucc., Myricaceae) showed in vitro testosterone 5alpha-reductase inhibitory activity and in vivo anti-androgenic activity using growth of flank organ in castrated Syrian hamsters and/or hair regrowth after shaving in testosterone-treated C57Black/6CrSlc mice. Three constituents, myricanone, myricanol, and myricetin were identified as the main active principles.
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ورودعنوان ژورنال:
- Biological & pharmaceutical bulletin
دوره 24 3 شماره
صفحات -
تاریخ انتشار 2001